Polynosological effects of ursodeoxycholic acid (UDCA). Practice of using
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چکیده
منابع مشابه
Ursodeoxycholic Acid (UDCA) in Biliary Diseases: A Clinical Review
Ursodeoxycholic acid (UDCA) is an established and accepted treatment of biliary diseases such as gallstones and primary biliary cirrhosis. Mechanisms of action of UDCA are not so far completely elucidated. UDCA tablets are indicated for the dissolution of small to medium sized radiolucent, cholesterol-rich gall-stones in patients with a functioning gall bladderand in the treatment of primary bi...
متن کاملTherapeutic and Chemopreventive Effects of Ursodeoxycholic Acid (UDCA): Potential Role in Patients with Barrett’s Esophagus
Instructor, Department of Internal Medicine, University of Texas Southwestern Medical Center and Dallas VA Medical Center, Esophageal Diseases Center, Dallas, Texas 75216, USA *Corresponding author Xiaofang Huo, MD, PhD Instructor Department of Internal Medicine University of Texas Southwestern Medical Center and Dallas VA Medical Center, Esophageal Diseases Center Dallas, Texas 75216, USA E-ma...
متن کاملUrsodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting RAGE Signaling in Diabetic Atherosclerosis
A naturally occurring bile acid, ursodeoxycholic acid (UDCA), is known to alleviate endoplasmic reticulum (ER) stress at the cellular level. However, the detailed action mechanisms of UDCA in atherosclerosis are not fully understood. In this study, we demonstrated whether UDCA exerts anti-atherogenic activity in diabetic atherosclerosis by targeting ER stress and "receptor for advanced glycatio...
متن کاملMethotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis.
This placebo-controlled, randomized, multicenter trial compared the effects of MTX plus UDCA to UDCA alone on the course of primary biliary cirrhosis (PBC). Two hundred and sixty five AMA positive patients without ascites, variceal bleeding, or encephalopathy; a serum bilirubin less than 3 mg/dL; serum albumin 3 g/dL or greater, who had taken UDCA 15 mg/kg daily for at least 6 months, were stra...
متن کاملWaking Action of Ursodeoxycholic Acid (UDCA) Involves Histamine and GABAA Receptor Block
Since ancient times ursodeoxycholic acid (UDCA), a constituent of bile, is used against gallstone formation and cholestasis. A neuroprotective action of UDCA was demonstrated recently in models of Alzheimer's disease and retinal degeneration. The mechanisms of UDCA action in the nervous system are poorly understood. We show now that UDCA promotes wakefulness during the active period of the day,...
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ژورنال
عنوان ژورنال: Medical Council
سال: 2016
ISSN: 2079-701X
DOI: 10.21518/2079-701x-2016-14-62-67